Sunday, January 6, 2008

Typical Justification and who does it (Stanford)

Biomedical Informatics

Translational Bioinformatics

It is the responsibility of those of us involved in today's biomedical research enterprise to translate the remarkable scientific innovations we are witnessing into health gains for the nation… At no other time has the need for a robust, bidirectional information flow between basic and translational scientists been so necessary.

Elias A. Zerhouni, M.D.,
Director, National Institutes of Health
New England Journal of Medicine, 353:1621, 2005


Translational Bioinformatics is the development of analytic, storage, and interpretive methods to optimize the transformation of increasingly voluminous genetic, genomic, and biological data into diagnostics and therapeutics for medicine. Topics covered in this course:
Access and utility of publicly available data sources
Types of genome-scale measurements in molecular biology and genomic medicine
Analysis of microarray data
Analysis of polymorphisms, proteomics, and protein interactions
Linking genome-scale data to clinical data and phenotypes
New questions in biomedicine using bioinformatics. Case studies.

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